After the events of Captain America: Civil War, Peter Parker, with the help of his mentor Tony Stark, tries to balance his life as an ordinary high school student in New York with fighting crime as his superhero alter ego Spider-Man as a new threat, the Vulture, emerges.

In a crime-ridden city, a fatally wounded cop returns to the force as a powerful cyborg with submerged memories haunting him.

Having defeated the Joker, Batman now faces the Penguin - a warped and deformed individual who is intent on being accepted into Gotham society. Crooked businessman Max Schreck is coerced into helping him become Mayor of Gotham and they both attempt to expose Batman in a different light. Selina Kyle, Max's secretary, is thrown from the top of a building and is transformed into Catwoman - a mysterious figure who has the same personality disorder as Batman. Batman must attempt to clear his name, all the time deciding just what must be done with the Catwoman.

The Dark Knight of Gotham City begins his war on crime with his first major enemy being the clownishly homicidal Joker, who has seized control of Gotham's underworld.