Following the events of Age of Ultron, the collective governments of the world pass an act designed to regulate all superhuman activity. This polarizes opinion amongst the Avengers, causing two factions to side with Iron Man or Captain America, which causes an epic battle between former allies

The brash-but-brilliant industrialist Tony Stark/Iron Man is faced against an enemy whose reach knows no bounds. When Stark finds his personal world destroyed at his enemy’s hands, he embarks on a harrowing quest to find those responsible. This journey, at every turn, will test his mettle. With his back against the wall, Stark is left to survive by his own devices, relying on his ingenuity and instincts to protect those closest to him. As he fights his way back, Stark discovers the answer to the question that has secretly haunted him: does the man make the suit or does the suit make the man?

Now that his Super Hero secret has been revealed, Tony Stark's life is more intense than ever. Everyone wants in on the Iron Man technology, whether for power or profit... But for Ivan Vanko, it's revenge! Tony must once again suit up and face his most dangerous enemy yet, but not without a few new allies of his own.

When contact is lost with the crew of the first Mars expedition, a rescue mission is launched to discover their fate.