Since the dawn of civilization, he was worshipped as a god. Apocalypse, the first and most powerful mutant from Marvel’s X-Men universe, amassed the powers of many other mutants, becoming immortal and invincible. Upon awakening after thousands of years, he is disillusioned with the world as he finds it and recruits a team of powerful mutants, including a disheartened Magneto, to cleanse mankind and create a new world order, over which he will reign. As the fate of the Earth hangs in the balance, Raven with the help of Professor X must lead a team of young X-Men to stop their greatest nemesis and save mankind from complete destruction.

"Days of Future Past" is a popular storyline in the Marvel Comics comic book The Uncanny X-Men issues #141 and #142, published in 1981. It deals with a dystopian alternative future in which mutants are incarcerated in internment camps. An older Kitty Pryde transfers her mind into the younger, present-day Kitty Pryde, who brings the X-Men to prevent a fatal moment in history which triggers anti-mutant hysteria.

Set 5 years after the end of Superman II, the film begins when Superman returns to discover his absence allowed Lex Luthor to walk free, and that those he was closest too felt abandoned and have moved on. Luthor plots his ultimate revenge that could see millions killed and change the face of the planet forever, as well as ridding himself of the caped crusader.

Professor Charles Xavier and his team of genetically gifted superheroes face a rising tide of anti-mutant sentiment led by Col. William Stryker in this sequel to the Marvel Comics-based blockbuster X-Men. Storm, Wolverine and Jean Grey must join their usual nemeses Magneto and Mystique to unhinge Stryker's scheme to exterminate all mutants.

Two mutants, Rogue and Wolverine, come to a private academy for their kind whose resident superhero team, the X-Men, must oppose a terrorist organization with similar powers.