40 years from today, Berlin is a roiling city of immigrants, where East crashes against West in a science-fiction Casablanca. Leo Beiler (Skarsgard), a mute bartender, has one reason and one reason only for living there, and she's disappeared. But when Leo's search takes him deeper into the city's underbelly, an odd pair of American surgeons (led by Rudd) seem to be the only recurring clue, and Leo can't tell if they can help, or who he should fear most.